Krt19-2A-Cre
品系全名
C57BL/6Smoc-Krt19em1(2A-Cre-WPRE-pA)Smoc
目录号
NM-KI-242885
品系状态
活体
基因信息
基因名
Krt19
品系描述
验证数据
Fig1. Cre mediated recombination in large intestine of Krt19 Cre/+;Rosa26 tdTomato/+ mice.
Fig2. Detection of tdTomato(red) in various tissues of Krt19 Cre/+;Rosa26 tdTomato/+ mice. Tissue distribution of tdTomato expression: Heart, liver, small intestine, large intestine, stomach, pancreas, reproductive system, skin, prostate, uterus. (4-weeks old, female; 5-weeks old, male) (For more detailed information please contact our technical advisor.)
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Cre-ERT2在无Tamoxifen诱导的情况下,在细胞质内处于无活性状态;当Tamoxifen诱导后,Tamoxifen的代谢产物4-OHT(雌激素类似物)与ERT结合,可使Cre-ERT2进核发挥Cre重组酶活性。
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