南模生物具有多年的PDX构建经验,借助重度免疫缺陷小鼠M-NSG的高成瘤率,已成功构建大量PDX模型,覆盖全身各类组织器官,可为您提供专业高效的PDX模型构建服务。
CDX肿瘤模型案例
Fig. In situ transplantation tumour model based on HepG2-Luc hepatocellular carcinoma cells (host mouse: M-NSG). a. Model tumourigenic curve versus body weight curve; b. Photograph of mouse liver; c. Mouse live imaging image.
Fig. Lung in situ graft tumour model constructed based on the human SHP-77-Luc lung cancer cell line.
Fig. Pancreatic in situ graft tumour model constructed based on the human PANC-1-Luc pancreatic cancer cell line.
Fig. Cervical transplantation in situ tumour model constructed based on the human Hela-Luc cervical cancer cell line.
Fig. In situ graft tumour model of glioma constructed based on the human U87MG glioma cell line.
Fig. In situ transplant tumour model of bladder cancer constructed based on the human RT112-Luc bladder cancer cell line.
Fig. Femoral injection bone metastasis model constructed based on the human MDA-MB-231-Luc breast cancer cell line.
CDX肿瘤药效案例
Fig. Anti-tumour drug efficacy validation experiments using the CDX model of ovarian cancer cell line (SK-OV-3).
Fig. CAR-T cell therapy efficacy validation experiment using lung cancer cell line (A549) CDX model.
Fig. mRNA anti-tumor drug efficacy validation experiments using the CDX model of the B-lymphoblastic leukaemia cell line (Nalm6-Luc).