Adora2a-CreERT2
品系全名
C57BL/6Smoc-Adora2aem1(Kozak-CreERT2-WPRE-pA)Smoc
目录号
NM-KI-241092
品系状态
精子冻存
基因信息
基因名
Adora2a
品系描述
将Kozak-CreERT2-WPRE-pA插入到小鼠Adora2a基因起始密码子处。
*使用本品系发表的文献需注明: Adora2a-CreERT2 mice (Cat. NO. NM-KI-241092) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig 1. CreERT2-mediated recombination in brain of Adora2aCreERT2/+; Rosa26tdTomato/+ mice.
Fig 2. Detection of tdTomato (red) in various tissues of Adora2aCreERT2/+; Rosa26tdTomato/+ mice. Tissue distribution of tdTomato expression: brain, eye, lung, liver, salivary gland, thymus, bone marrow, kidney, pancreas, small intestine, spleen, reproductive system, mesenteric lymph nodes. (45-days old, female) (For more detailed information please contact our technical advisor.)
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Tamoxifen诱导Cre-ERT2小鼠 使用指南
Cre-ERT2在无Tamoxifen诱导的情况下，在细胞质内处于无活性状态；当Tamoxifen诱导后，Tamoxifen的代谢产物4-OHT（雌激素类似物）与ERT结合，可使Cre-ERT2进核发挥Cre重组酶活性。
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