hIL1RL1/hTSLP

品系全名

C57BL/6Smoc-Il1rl1tm4(hIL1RL1)Tslptm2(hTSLP)Smoc

目录号

NM-XA-241614

品系状态

活体

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基因信息

基因名
TSLP

基因曾用名

NCBI ID

53603

MGI ID

1855696

Ensembl ID

ENSMUSG00000024379

Pubmed

TSLP

人类同源基因

TSLP

品系描述

通过hTSLP(NM-HU-2000064)与hIL1RL1(NM-HU-2000067)小鼠交配获得。

验证数据

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Fig.1 Exprssion analysis of of hIL1RL1 on Treg cells in spleen in hIL1RL1/hTSLP mice. Leukocytes were collected from the spleens of 9-week-old wild-type C57BL/6 mice (WT) and hIL1RL1/hTSLP mice, and analyzed by flow cytometry with anti-hIL1RL1 antibody and anti-mIL1RL1 antibody. hIL1RL1 was exclusively detectable on Treg in hIL1RL1/hTSLP mice, whereas mIL1RL1 was exclusively detectable on Treg in wild-type C57BL/6 mice.

image.png

Fig.2 Expression of hIL1RL1 on FcεRIα+ cells in Bone marrow in hIL1RL1/hTSLP mice. Leukocytes were collected from the bone marrow of 9-week-old wild-type C57BL/6 mice (WT) and hIL1RL1/hTSLP mice, and analyzed by flow cytometry with anti-hIL1RL1 antibody and anti-mIL1RL1 antibody. hIL1RL1 was exclusively detectable on FcεRIα+ cells in hIL1RL1/hTSLP mice, whereas mIL1RL1 was exclusively detectable on FcεRIα+ cells in wild-type C57BL/6 mice.

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