支持多种样品类型
能够处理骨髓、脑脊液、不同抗凝剂处理的血浆、细胞裂解液、细胞上清液等多种复杂样本
支持微量样品检测
流式可低至纳米级颗粒或10 μL上样体积，ELISA可检出fg/mL级别的生物标志物，可检出20万-30万中的1个阳性细胞
分析检测速度快，灵敏度高
流式上样速度高达30,000 events/s；ELISA支持四通道荧光成像和明场成像
体外药效检测平台
服务项目
服务案例
Fig. FACS detection of immune cell infiltration in subcutaneous graft tumours.(**P<0.01,*P<0.05)
SMOC provides a comprehensive portfolio of predefifined cytokine panels, offffering flflexible selection aligned with drug mechanisms and experimental objectives. Our assays achieve high sensitivity down to 10 pg/mL, with select ultra-sensitive platforms reaching 274 fg/mL. Detection covers diverse biospecimens—including serum, plasma, tears, aqueous humor, saliva, body cavity lavage flfluids, cell supernatants, and tissue lysates—across mouse, rat, non-human primate, and human for immunology, oncology, neurology, and functional research.
服务项目
服务案例
服务项目
服务案例
The mixed lymphocyte reaction (MLR) is commonly used to determine the degree of compatibility between the major histocompatibility complex (HLA) antigens of a recipient and a donor. It is a system involving the co-culture of primary dendritic cells (DCs) and T cells, and is frequently used to assess DC-mediated T cell activation.
Sample: mDC+CD4+T cells+Compound
Vehicle control: mDC+CD4+T cells+Medium
Medium: Medium
Antibody-based therapies often require the use of the complement-dependent cytolysis (CDC) assay to evaluate their efficacy. The CDC assay assesses the ability of a candidate drug to destroy specific target cells through multiple pathways mediated by the complement system.
The CDC assay typically involves incubating target cells, the antibody under test, and serum (as a source of complement) together at 37°C for 1–24 hours, after which the lysed dead cells or live cells can be examined.
Antibody-dependent cellular cytotoxicity (ADCC) is a key immune mechanism in which effector cells lyse target cells via membrane surface antigens bound by specific antibodies; it also forms the basis for many current antibody therapies.
When the drug in an ADC is released after being internalized and degraded within the target cell, or when it is released into the extracellular space, it induces bystander killing, which is one of the key mechanisms by which ADCs exert their effects.
