M-NSG

1. Shear stress governs hematopoietic stem cell fate to promote inflammation-induced aging
发表年份：2026 来源杂志：Nature Aging

2. FOSL1 Orchestrates Epigenetic Reprogramming of Anaplastic Thyroid Cancer and Suppresses Natural Killer Cell-Mediated Antitumor Immunity
发表年份：2026 来源杂志：CANCER RESEARCH

3. Structure–Activity-Driven Multicompartment Lipid Nanoparticles for Synergistic mRNA and siRNA Codelivery in Acute Myeloid Leukemia
发表年份：2026 来源杂志：Journal of the American Chemical Society

4. Apoptotic bodies derived from human umbilical cord mesenchymal stem cells improve recovery from myocardial infarction in swine
发表年份：2026 来源杂志：Autophagy

5. ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC-I Antigen Presentation That Promotes Tumor Immune Evasion
发表年份：2026 来源杂志：Advanced Science

6. PD-L1-Binding Antigen Presenters: Redirecting Vaccine-Induced Antibodies for Cancer Immunotherapy
发表年份：2026 来源杂志：Advanced Science

7. Vessels encapsulating tumor clusters promote non-invasive metastasis of hepatocellular carcinoma by shaping an immunosuppressive microenvironment
发表年份：2026 来源杂志：JOURNAL OF CLINICAL INVESTIGATION

8. Genome-wide screenings identify BAP1 as a synthetic-lethality target with CDK4/6 inhibitors
发表年份：2026 来源杂志：Science Advances

9. mRNA lipid-nanoparticle-mediated mitochondrial apoptosis augments adoptive T cell immunotherapy
发表年份：2026 来源杂志：Cell Reports Medicine

10. USP20, a Super-enhancer Regulated Gene, Promotes Acute Myeloid Leukemia Progression through CTNNB1 Deubiquitination
发表年份：2026 来源杂志：International Journal of Biological Sciences

11. Unleashing T cell surveillance for the eradication of quiescent persister tumor cells resistant to neoadjuvant chemotherapy
发表年份：2026 来源杂志：DEVELOPMENTAL CELL

12. A shark VNAR-IL-15 fusion protein that suppresses TROP2+ tumor growth
发表年份：2026 来源杂志：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

13. Silencing SFRP1 in bone mesenchymal stem cells alleviates pediatric B-ALL-driven bone loss by activating Wnt/β-catenin signaling
发表年份：2026 来源杂志：Journal of Orthopaedic Translation

14. Metabolic reinvigoration of NK cells by IL-21 enhances immunotherapy against MHC class I-deficient solid tumors
发表年份：2026 来源杂志：Cell Reports

15. Discovery of Oxime Ether Derivatives as Second-Generation PRMT5 Inhibitors for the Treatment of Triple Negative Breast Cancer
发表年份：2026 来源杂志：JOURNAL OF MEDICINAL CHEMISTRY

16. Halofuginone exerts broad-spectrum cytotoxic effects by regulating p-eIF2α-S100A8/A9-calcium signaling, inhibiting global protein synthesis, and reversing the resistance of idarubicin in acute myeloid leukemia
发表年份：2026 来源杂志：Chinese Medicine

17. Multi-omics classification of acute myeloid leukemia guides drug combinations to overcome Venetoclax resistance
发表年份：2026 来源杂志：Cancer Drug Resistance

18. ERCC6L promotes cutaneous melanoma progression via PLK1-mediated aerobic glycolysis: Mechanisms and therapeutic implications
发表年份：2026 来源杂志：LIFE SCIENCES

19. A novel human acute myeloid leukemia cell line SDEY-AML1 with KMT2A: MLLT3, IKZF1: EVX1 fusions exhibits high tumorigenicity in NSG mice
发表年份：2026 来源杂志：Scientific Reports

20. Preclinical Evaluation of AHT-102, a CLDN18.2 × CD3 Bispecific Antibody: Pharmacokinetics, Anti-Tumor Efficacy, Tissue Distribution, and Safety Profile
发表年份：2026 来源杂志：DRUGS IN R&D

21. Cytosolic acetyl-coenzyme A is a signalling metabolite to control mitophagy
发表年份：2025 来源杂志：NATURE

22. Prickle4 Drives Microenvironmental Remodeling and Resistance to Parp Inhibition in IDH-Mutant Glioma
发表年份：2025 来源杂志：Advanced Science

23. JMJD3 upregulates ALOX5 to drive malignancy and concomitant ferroptosis sensitivity in gastric cancer
发表年份：2025 来源杂志：Cell Death & Disease

24. Low SVEP1 in intrahepatic cholangiocarcinoma mediates phenotype switching-driven metastasis by Jag2/Notch1/Hes5
发表年份：2025 来源杂志：Cell Death & Disease

25. Coke Oven Emission Exposure Triggers Malignant Transformation of Lung Epithelial Cells by SFTA1P-Dependent Alteration of Acetyl-CoA Metabolism
发表年份：2025 来源杂志：Environment & Health

26. Chemical induction of ferroptosis through GPX4 inhibition: Rational Design of Triazole-Benzoxazine Hybrids for melanoma therapy
发表年份：2025 来源杂志：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

27. Preclinical Development and a Case Report of a Nanobody-Based CLDN18.2 CAR-T IMC002 with Reduced On-Target Off-Tumor Toxicity
发表年份：2025 来源杂志：MOLECULAR CANCER THERAPEUTICS

28. Demethylzeylasteral alleviates myeloid leukemia through PERK/eIF2α/ATF4/CHOP-mediated cell apoptosis
发表年份：2025 来源杂志：Translational Cancer Research

29. Targeting tumor-intrinsic S100 calcium-binding protein A1 augments antitumor immunity and potentiates immunotherapy efficacy
发表年份：2025 来源杂志：Signal Transduction and Targeted Therapy

30. A collagenase nanogel backpack improves CAR-T cell therapy outcomes in pancreatic cancer
发表年份：2025 来源杂志：Nature Nanotechnology

31. CircABCA1 promotes ccRCC by reprogramming cholesterol metabolism and facilitating M2 macrophage polarization through IGF2BP3-mediated stabilization of SCARB1 mRNA
发表年份：2025 来源杂志：Molecular Cancer

32. Foxp3 confers long-term efficacy of chimeric antigen receptor-T cells via metabolic reprogramming
发表年份：2025 来源杂志：Cell Metabolism

33. Arachidonic acid triggers spermidine synthase secretion from primary tumor to induce skeletal muscle weakness upon irradiation
发表年份：2025 来源杂志：Cell Metabolism

34. Bispecific killer cell engager-secreting CAR-T cells redirect natural killer specificity to enhance antitumour responses
发表年份：2025 来源杂志：Nature Biomedical Engineering

35. Inhibition of tumor cell macropinocytosis driver DHODH reverses immunosuppression and overcomes anti-PD1 resistance
发表年份：2025 来源杂志：IMMUNITY

36. Clinical functional proteomics of intercellular signalling in pancreatic cancer
发表年份：2024 来源杂志：NATURE

37. Targeting the immune privilege of tumor-initiating cells to enhance cancer immunotherapy
发表年份：2024 来源杂志：CANCER CELL

38. Lyophilized lymph nodes for improved delivery of chimeric antigen receptor T cells
发表年份：2024 来源杂志：NATURE MATERIALS

39. An oncolytic virus–T cell chimera for cancer immunotherapy
发表年份：2024 来源杂志：NATURE BIOTECHNOLOGY

40. The N6-methyladenosine Epitranscriptomic Landscape of Lung Adenocarcinoma
发表年份：2024 来源杂志：Cancer Discovery

41. Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
发表年份：2024 来源杂志：Cell Metabolism

42. Dietary elaidic acid boosts tumoral antigen presentation and cancer immunity via ACSL5
发表年份：2024 来源杂志：Cell Metabolism

43. A novel peptide PDHK1-241aa encoded by circPDHK1 promotes ccRCC progression via interacting with PPP1CA to inhibit AKT dephosphorylation and activate the AKT-mTOR signaling pathway
发表年份：2024 来源杂志：Molecular Cancer

44. Photo-metallo-immunotherapy: Fabricating Chromium-Based Nanocomposites to Enhance CAR-T Cell Infiltration and Cytotoxicity against Solid Tumors
发表年份：2024 来源杂志：ADVANCED MATERIALS

45. An Oral PROTAC Targeting HPK1 Degradation Potentiates Anti-Solid Tumor Immunity
发表年份：2024 来源杂志：ADVANCED MATERIALS

46. Enhanced engraftment of human haematopoietic stem cells via mechanical remodelling mediated by the corticotropin-releasing hormone
发表年份：2024 来源杂志：Nature Biomedical Engineering

47. Vasopressin drives aberrant myeloid differentiation of hematopoietic stem cells, contributing to depression in mice
发表年份：2024 来源杂志：Cell Stem Cell

48. FLI1 promotes IFN-γ-induced kynurenine production to impair anti-tumor immunity
发表年份：2024 来源杂志：Nature Communications

49. Acetylation-dependent regulation of core spliceosome modulates hepatocellular carcinoma cassette exons and sensitivity to PARP inhibitors
发表年份：2024 来源杂志：Nature Communications

50. PJA1-mediated suppression of pyroptosis as a driver of docetaxel resistance in nasopharyngeal carcinoma
发表年份：2024 来源杂志：Nature Communications

51. Ultrasound Control of Genomic Regulatory Toolboxes for Cancer Immunotherapy
发表年份：2024 来源杂志：Nature Communications

52. Tumor-derived miR-9-5p-loaded EVs regulate cholesterol homeostasis to promote breast cancer liver metastasis in mice
发表年份：2024 来源杂志：Nature Communications

53. Specific surface-modified iron oxide nanoparticles trigger complement-dependent innate and adaptive antileukaemia immunity
发表年份：2024 来源杂志：Nature Communications

54. Succinate dehydrogenase deficiency-driven succinate accumulation induces drug resistance in acute myeloid leukemia via ubiquitin-cullin regulation
发表年份：2024 来源杂志：Nature Communications

55. Split-design approach enhances the therapeutic efficacy of ligand-based CAR-T cells against multiple B-cell malignancies
发表年份：2024 来源杂志：Nature Communications

56. ATP6V1D drives hepatocellular carcinoma stemness and progression via both lysosome acidification-dependent and -independent mechanisms
发表年份：2024 来源杂志：Autophagy

57. Protein Kinase STK24 Promotes Tumor Immune Evasion via the AKT-PD-L1 Axis
发表年份：2024 来源杂志：Advanced Science

58. Kidney Organoid Modeling of WT1 Mutations Reveals Key Regulatory Paths Underlying Podocyte Development
发表年份：2024 来源杂志：Advanced Science

59. SIN3B Loss Heats up Cold Tumor Microenvironment to Boost Immunotherapy in Pancreatic Cancer
发表年份：2024 来源杂志：Advanced Science

60. SKAP1 Expression in Cancer Cells Enhances Colon Tumor Growth and Impairs Cytotoxic Immunity by Promoting Neutrophil Extracellular Trap Formation via the NFATc1/CXCL8 Axis
发表年份：2024 来源杂志：Advanced Science

61. A pan-KRAS degrader for the treatment of KRAS-mutant cancers
发表年份：2024 来源杂志：Cell Discovery

62. ADAR1 is required for acute myeloid leukemia cell survival by modulating post-transcriptional Wnt signaling through impairing miRNA biogenesis
发表年份：2024 来源杂志：LEUKEMIA

63. Anagrelide and idarubicin combination induces GSDME-mediated pyroptosis as a potential therapy for high-PDE3A acute myeloid leukemia
发表年份：2024 来源杂志：LEUKEMIA

64. Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
发表年份：2024 来源杂志：CANCER RESEARCH

65. Targeting SHCBP1 Inhibits Tumor Progression by Restoring Ciliogenesis in Ductal Carcinoma
发表年份：2024 来源杂志：CANCER RESEARCH

66. Adhesion GPCR ADGRE2 Maintains Proteostasis to Promote Progression in Acute Myeloid Leukemia
发表年份：2024 来源杂志：CANCER RESEARCH

67. HDAC6-dependent deacetylation of NGF dictates its ubiquitination and maintains primordial follicle dormancy
发表年份：2024 来源杂志：Theranostics

68. Integrated multi-omics reveal gut microbiota-mediated bile acid metabolism alteration regulating immunotherapy responses to anti-α4β7-integrin in Crohn’s disease
发表年份：2024 来源杂志：Gut Microbes

69. Venetoclax acts as an immunometabolic modulator to potentiate adoptive NK cell immunotherapy against leukemia
发表年份：2024 来源杂志：Cell Reports Medicine

70. Enhancer looping protein LDB1 modulates MYB expression in T-ALL cell lines in vitro by cooperating with master transcription factors
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

71. Integrated stress response activation induced by usnic acid alleviates BCL-2 inhibitor ABT-199 resistance in acute myeloid leukemia
发表年份：2024 来源杂志：Journal of Advanced Research

72. Rationally designed BCR-ABL kinase inhibitors for improved leukemia treatment via covalent and pro-/dual-drug targeting strategies
发表年份：2024 来源杂志：Journal of Advanced Research

73. Targeting RBM39 through indisulam induced mis-splicing of mRNA to exert anti-cancer effects in T-cell acute lymphoblastic leukemia
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

74. LILRB4 on multiple myeloma cells promotes bone lesion by p-SHP2/NF-κB/RELT signal pathway
发表年份：2024 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

75. iPSC-derived NK cells with site-specific integration of CAR19 and IL24 at the multi-copy rDNA locus enhanced antitumor activity and proliferation
发表年份：2024 来源杂志：MedComm

76. Glutathione-depleting Liposome Adjuvant for Augmenting the Efficacy of a Glutathione Covalent Inhibitor Oridonin for Acute Myeloid Leukemia Therapy
发表年份：2024 来源杂志：JOURNAL OF NANOBIOTECHNOLOGY

77. RCAd-LTH-shPD-L1, a double-gene recombinant oncolytic adenovirus with enhanced antitumor immunity, increases lymphocyte infiltration and reshapes the tumor microenvironment
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

78. ICOS-expressing CAR-T cells mediate durable eradication of triple-negative breast cancer and metastasis
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

79. ImmunoPET imaging of LAG-3 expression in tumor microenvironment with 68Ga-labelled cyclic peptides tracers: from bench to bedside
发表年份：2024 来源杂志：Journal for ImmunoTherapy of Cancer

80. Restoring T and B cell generation in X-linked severe combined immunodeficiency mice through hematopoietic stem cells adenine base editing
发表年份：2024 来源杂志：MOLECULAR THERAPY

81. Mid1 promotes synovitis in rheumatoid arthritis via ubiquitin-dependent post-translational modification
发表年份：2024 来源杂志：PHARMACOLOGICAL RESEARCH

82. miR-590-3p Overexpression Improves the Efficacy of hiPSC-CMs for Myocardial Repair
发表年份：2024 来源杂志：JACC-Basic to Translational Science

83. Cisplatin-induced Pyroptosis Enhances the Efficacy of PD-L1 Inhibitor in Small-Cell Lung Cancer via GSDME/IL12/CD4Tem Axis
发表年份：2024 来源杂志：International Journal of Biological Sciences

84. LncRNA ZNF674-AS1 drives cell growth and inhibits cisplatin-induced pyroptosis via up-regulating CA9 in neuroblastoma
发表年份：2024 来源杂志：Cell Death & Disease

85. Histidine re-sensitizes pediatric acute lymphoblastic leukemia to 6-mercaptopurine through tetrahydrofolate consumption and SIRT5-mediated desuccinylation
发表年份：2024 来源杂志：Cell Death & Disease

86. Small extracellular vesicle piR-hsa-30937 derived from pancreatic neuroendocrine neoplasms upregulates CD276 in macrophages to promote immune evasion
发表年份：2024 来源杂志：Cancer Immunology Research

87. Targeting high circDNA2v levels in colorectal cancer induces cellular senescence and elicits an anti-tumor secretome
发表年份：2024 来源杂志：Cell Reports

88. Small-molecule α-lipoic acid targets ELK1 to balance human neutrophil and erythrocyte differentiation
发表年份：2024 来源杂志：Stem Cell Research & Therapy

89. Dehydrocostus lactone alleviates irinotecan-induced intestinal mucositis by blocking TLR4/MD2 complex formation
发表年份：2024 来源杂志：PHYTOMEDICINE

90. Lactate/GPR81 recruits regulatory T cells by modulating CX3CL1 to promote immune resistance in a highly glycolytic gastric cancer
发表年份：2024 来源杂志：OncoImmunology

91. PHE1-based IgG-like antibody platform provides a novel strategy for enhanced T-cell immunotherapy
发表年份：2024 来源杂志：Frontiers in Immunology

92. INPP4B suppresses HER2-induced mesenchymal transition in HER2+ breast cancer and enhances sensitivity to Lapatinib
发表年份：2024 来源杂志：BIOCHEMICAL PHARMACOLOGY

93. The CDK4/6 inhibitor Palbociclib synergizes with ATRA to induce differentiation in AML
发表年份：2024 来源杂志：MOLECULAR CANCER THERAPEUTICS

94. TYM-3-98, a novel selective inhibitor of PI3Kδ, demonstrates promising preclinical antitumor activity in B-cell lymphomas
发表年份：2024 来源杂志：LIFE SCIENCES

95. FAM120A deficiency improves resistance to cisplatin in gastric cancer by promoting ferroptosis
发表年份：2024 来源杂志：Communications Biology

96. IMT030122, A novel engineered EpCAM/CD3/4-1BB tri-specific antibody, enhances T-cell recruitment and demonstrates anti-tumor activity in mouse models of colorectal cancer
发表年份：2024 来源杂志：INTERNATIONAL IMMUNOPHARMACOLOGY

97. ARID5A stabilizes Indoleamine 2,3-dioxygenase expression and enhances CAR T cell exhaustion in colorectal cancer
发表年份：2024 来源杂志：Translational Oncology

98. HDAC inhibitors target IRS4 to enhance anti‑AR therapy in AR‑positive triple‑negative breast cancer
发表年份：2024 来源杂志：INTERNATIONAL JOURNAL OF ONCOLOGY

99. Preclinical evaluation of the theranostic potential of 89Zr/177Lu-labeled anti-TROP-2 antibody in triple-negative breast cancer model
发表年份：2024 来源杂志：EJNMMI Radiopharmacy and Chemistry

100. Effective in vivo reactivation of HIV-1 latency reservoir via oral administration of EK-16A-SNEDDS
发表年份：2024 来源杂志：EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

101. PLA2G2D promotes immune escape in non-small cell lung cancer by regulating T cell immune function through PD-L1-expressing extracellular vesicles
发表年份：2024 来源杂志：SCANDINAVIAN JOURNAL OF IMMUNOLOGY

102. Discovery of Phenylpyrazole Derivatives as a New Class of Selective Inhibitors of MCL-1 with Antitumor Activity
发表年份：2024 来源杂志：ACS Omega

103. FYB1-targeted modulation of CAPG promotes AML progression
发表年份：2024 来源杂志：MOLECULAR AND CELLULAR BIOCHEMISTRY

104. PANoptosis Features, a Humanized NSG Murine Model of Sjogren's Syndrome
发表年份：2024 来源杂志：DNA AND CELL BIOLOGY

105. Regional delivery of mesothelin-targeted chimeric antigen receptor T-cell effectively and safely targets colorectal cancer liver metastases in mice
发表年份：2024 来源杂志：Journal of Gastrointestinal Oncology

106. Exosome-derived circCCAR1 promotes CD8+T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
发表年份：2023-03-18 来源杂志：Molecular Cancer

107. Chemokine Receptors CCR6 and PD1 Blocking scFv E27 Enhances Anti-EGFR CAR-T Therapeutic Efficacy in a Preclinical Model of Human Non-Small Cell Lung Carcinoma
发表年份：2023-03-12 来源杂志：International Journal of Molecular Sciences

108. A novel antidiuretic hormone governs tumour-induced renal dysfunction
发表年份：2023 来源杂志：NATURE

109. Prolonged sleep deprivation induces a cytokine-storm-like syndrome in mammals
发表年份：2023 来源杂志：CELL

110. Imatinib blocks tyrosine phosphorylation of Smad4 and restores TGF-β growth-suppressive signaling in BCR-ABL1-positive leukemia
发表年份：2023 来源杂志：Signal Transduction and Targeted Therapy

111. Exosome-derived circCCAR1 promotes CD8 + T-cell dysfunction and anti-PD1 resistance in hepatocellular carcinoma
发表年份：2023 来源杂志：Molecular Cancer

112. Tumors evade immune cytotoxicity by altering the surface topology of NK cells
发表年份：2023 来源杂志：NATURE IMMUNOLOGY

113. Targeting UBE2T Potentiates Gemcitabine Efficacy in Pancreatic Cancer by Regulating Pyrimidine Metabolism and Replication Stress
发表年份：2023 来源杂志：GASTROENTEROLOGY

114. Bone marrow immune cells respond to fluctuating nutritional stress to constrain weight regain
发表年份：2023 来源杂志：Cell Metabolism

115. The BCL-2 inhibitor APG-2575 resets tumor-associated macrophages toward the M1 phenotype, promoting a favorable response to anti-PD-1 therapy via NLRP3 activation
发表年份：2023 来源杂志：Cellular & Molecular Immunology

116. STING is a cell-intrinsic metabolic checkpoint restricting aerobic glycolysis by targeting HK2
发表年份：2023 来源杂志：NATURE CELL BIOLOGY

117. Cyclosporine A-resistant CAR-T cells mediate antitumour immunity in the presence of allogeneic cells
发表年份：2023 来源杂志：Nature Communications

118. SCARB2 drives hepatocellular carcinoma tumor initiating cells via enhanced MYC transcriptional activity
发表年份：2023 来源杂志：Nature Communications

119. Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia
发表年份：2023 来源杂志：Nature Communications

120. Sequence-based drug design as a concept in computational drug design
发表年份：2023 来源杂志：Nature Communications

121. TRIM21 inhibits irradiation-induced mitochondrial DNA release and impairs antitumour immunity in nasopharyngeal carcinoma tumour models
发表年份：2023 来源杂志：Nature Communications

122. Low level of ARID1A contributes to adaptive immune resistance and sensitizes triple-negative breast cancer to immune checkpoint inhibitors
发表年份：2023 来源杂志：Cancer Communications

123. Enhancement of CAR-T cell activity against cholangiocarcinoma by simultaneous knockdown of six inhibitory membrane proteins
发表年份：2023 来源杂志：Cancer Communications

124. Canagliflozin primes antitumor immunity by triggering PD-L1 degradation in endocytic recycling
发表年份：2023 来源杂志：JOURNAL OF CLINICAL INVESTIGATION

125. Cell autonomous expression of BCL6 is required to maintain lineage identity of mouse CCR6+ ILC3s
发表年份：2023 来源杂志：JOURNAL OF EXPERIMENTAL MEDICINE

126. CAR-Aptamers Enable Traceless Enrichment and Monitoring of CAR-Positive Cells and Overcome Tumor Immune Escape
发表年份：2023 来源杂志：Advanced Science

127. NIRF/PET imaging of γδ T cells via metabolic glycoengineering and bioorthogonal labeling
发表年份：2023 来源杂志：CHEMICAL ENGINEERING JOURNAL

128. Novel Human Meningioma Organoids Recapitulate the Aggressiveness of the Initiating Cell Subpopulations Identified by ScRNA-Seq
发表年份：2023 来源杂志：Advanced Science

129. Targeted therapy of central nervous system acute lymphoblastic leukemia with an integrin α6-targeted self-assembling proapoptotic nanopeptide
发表年份：2023 来源杂志：Engineering

130. Gut microbiota-related bile acid metabolism-FXR/TGR5 axis impacts the response to anti-α4β7-integrin therapy in humanized mice with colitis
发表年份：2023 来源杂志：Gut Microbes

131. Transcription factor Nkx2-3 maintains the self-renewal of hematopoietic stem cells by regulating mitophagy
发表年份：2023 来源杂志：LEUKEMIA

132. TRIM21 attenuates renal carcinoma lipogenesis and malignancy by regulating SREBF1 protein stability
发表年份：2023 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

133. Targeting the Immunoglobulin IGSF9 Enhances Antitumor T-cell Activity and Sensitivity to Anti–PD-1 Immunotherapy
发表年份：2023 来源杂志：CANCER RESEARCH

134. PICH activates Cyclin A1 transcription to drive S-phase progression and chemoresistance in gastric cancer.
发表年份：2023 来源杂志：CANCER RESEARCH

135. Faecalibacterium prausnitzii abrogates intestinal toxicity and promotes tumor immunity to increase the efficacy of dual CTLA-4 and PD-1 checkpoint blockade
发表年份：2023 来源杂志：CANCER RESEARCH

136. Targeted glycan degradation potentiates cellular immunotherapy for solid tumors
发表年份：2023 来源杂志：PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

137. Sitravatinib as a potent FLT3 inhibitor can overcome gilteritinib resistance in acute myeloid leukemia
发表年份：2023 来源杂志：Biomarker Research

138. TROP2-directed nanobody-drug conjugate elicited potent antitumor effect in pancreatic cancer
发表年份：2023 来源杂志：JOURNAL OF NANOBIOTECHNOLOGY

139. DNAJC10 maintains survival and self-renewal of leukemia stem cells through PERK branch of the unfolded protein response
发表年份：2023 来源杂志：HAEMATOLOGICA

140. T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
发表年份：2022-07-26 来源杂志：nature communications

141. A Chimeric Conjugate of Antibody and Programmable DNA Nanoassembly Smartly Activates T cell for Precise Cancer Cell Targeting
发表年份：2022-06-24 来源杂志：A Journal of the Gesellschaft Deutscher Chemiker

142. BSA-AIE Nanoparticles with Boosted ROS Generation for Immunogenic Cell Death Immunotherapy of Multiple Myeloma
发表年份：2022 来源杂志：ADVANCED MATERIALS

143. Synthetic libraries of immune cells displaying a diverse repertoire of chimaeric antigen receptors as a potent cancer immunotherapy
发表年份：2022 来源杂志：Nature Biomedical Engineering

144. T cell receptor β-chain-targeting chimeric antigen receptor T cells against T cell malignancies
发表年份：2022 来源杂志：Nature Communications

145. Malfunction of airway basal stem cells plays a crucial role in pathophysiology of tracheobronchopathia osteoplastica
发表年份：2022 来源杂志：Nature Communications

146. Modeling Human Thyroid Development by Fetal Tissue-Derived Organoid Culture
发表年份：2022 来源杂志：Advanced Science

147. Inhibition of Calcium Signaling Prevents Exhaustion and Enhances Anti-Leukemia Efficacy of CAR-T Cells via SOCE-Calcineurin-NFAT and Glycolysis Pathways
发表年份：2022 来源杂志：Advanced Science

148. Nano-Biohybrid DNA Engager That Reprograms the T-Cell Receptor
发表年份：2022 来源杂志：Journal of the American Chemical Society

149. Therapeutic strategies targeting uPAR potentiate anti–PD-1 efficacy in diffuse-type gastric cancer
发表年份：2022 来源杂志：Science Advances

150. Heliangin acts as a covalent ligand of RPS2 that disrupts pre-rRNA metabolic processes in NPM1-mutated acute myeloid leukemia
发表年份：2022 来源杂志：Acta Pharmaceutica Sinica B

151. An armed oncolytic virus enhances the efficacy of tumor-infiltrating lymphocyte therapy by converting tumors to artificial antigen-presenting cells in situ
发表年份：2022 来源杂志：MOLECULAR THERAPY

152. Single-cell ATAC-seq maps the comprehensive and dynamic chromatin accessibility landscape of CAR-T cell dysfunction
发表年份：2022 来源杂志：LEUKEMIA

153. FOXD1-dependent RalA-ANXA2-Src complex promotes CTC formation in breast cancer
发表年份：2022 来源杂志：JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

154. Deneddylation of PML/RARα reconstructs functional PML nuclear bodies via orchestrating phase separation to eradicate APL
发表年份：2022 来源杂志：CELL DEATH AND DIFFERENTIATION

155. Visualizing γδ T cells by very late antigen-4-targeted positron emission tomography
发表年份：2022 来源杂志：EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

156. Chemokine Receptor CCR2b Enhanced Anti-tumor Function of Chimeric Antigen Receptor T Cells Targeting Mesothelin in a Non-small-cell Lung Carcinoma Model
发表年份：2021-03-11 来源杂志：Front. Immunol

157. Bcl-2 Enhances Chimeric Antigen Receptor T Cell Persistence by Reducing Activation-Induced Apoptosis
发表年份：2021-01-08 来源杂志：Cancers

158. Liver type 1 innate lymphoid cells develop locally via an interferon-γ–dependent loop
发表年份：2021 来源杂志：SCIENCE

159. A chimeric antigen receptor with antigen-independent OX40 signaling mediates potent antitumor activity
发表年份：2021 来源杂志：Science Translational Medicine

160. The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability
发表年份：2021 来源杂志：MOLECULAR CELL

161. CAFs shape myeloid-derived suppressor cells to promote stemness of intrahepatic cholangiocarcinoma through 5-lipoxygenase
发表年份：2021 来源杂志：HEPATOLOGY

162. DMDRMR-Mediated Regulation of m6A-Modified CDK4 by m6A Reader IGF2BP3 Drives ccRCC Progression
发表年份：2021 来源杂志：CANCER RESEARCH

163. Fresh Tissue Multi-omics Profiling Reveals Immune Classification and Suggests Immunotherapy Candidates for Conventional Chondrosarcoma
发表年份：2021 来源杂志：CLINICAL CANCER RESEARCH

164. WSB1 regulates c-Myc expression through β-catenin signaling and forms a feedforward circuit
发表年份：2021 来源杂志：Acta Pharmaceutica Sinica B

165. TIGIT-Fc Promotes Antitumor Immunity
发表年份：2021 来源杂志：Cancer Immunology Research

166. 4-1BB Signaling Boosts the Anti-Tumor Activity of CD28-Incorporated 2nd Generation Chimeric Antigen Receptor-Modified T Cells
发表年份：2020-11-13 来源杂志：Frontiers in Immunology

167. SH3RF3 promotes breast cancer stem-like properties via JNK activation and PTX3 upregulation
发表年份：2020-05-19 来源杂志：NAT COMMUN

168. Peptide Self-Assembly Nanoparticles Loaded with Panobinostat to Activate Latent Human Immunodeficiency Virus
发表年份：2019-05-01 来源杂志：J Biomed Nanotechnol