hDKK1
品系全名
C57BL/6Smoc-Dkk1tm1(hDKK1)Smoc
目录号
NM-HU-234202
品系状态
活体
基因信息
基因名
Dkk1
品系描述
利用同源重组，将小鼠Dkk1基因进行人源化修饰。
*使用本品系发表的文献需注明: hDKK1 mice (Cat. NO. NM-HU-234202) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of DKK1 expression in thymus by RT-PCR. Thymus RNA was extracted from 11-week-old male WT C57BL/6 and homozygous hDKK1 knockin mice (n=3 in each group), then cDNA libraries were synthesized by reverse transcription, followed by PCR with mRNA primers. Mouse Dkk1 mRNA (426 bp) was detectable only in wild-type C57BL/6 mice. Human DKK1 mRNA (220 bp) was detectable only in homozygous hDKK1 knockin mice but not in wild-type mice.
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