hPCSK9(4)
品系全名
C57BL/6Smoc-Pcsk9tm4(hPCSK9)Smoc
目录号
NM-HU-251531
品系状态
精子冻存
基因信息
基因名
Pcsk9
品系描述
利用同源重组，将小鼠Pcsk9基因进行人源化修饰。
*使用本品系发表的文献需注明: hPCSK9(4) mice (Cat. NO. NM-HU-251531) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of human PCSK9 (A) expression in serum of WT C57BL/6 mice and HE hPCSK9(4) mice by ELISA. Human PCSK9 was exclusively detectable in heterozygous hPCSK9(4) knockin mice.Serum were collected from wild-type C57BL/6 mice (n=2, male, 12 weeks old) and HE hPCSK9(4) mice (n=3, male, 14 weeks old), and analyzed by ELISA with anti-hPCSK9 ELISA kit.
Abbr. HE, heterozygous; WT, wild type.
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