HLA-A24.2/B2M(M-NSG)
品系全名
NOD.Cg-PrkdcscidIl2rgem1B2mem1(hB2M-linker-HLA-A*2402/H2-D1)Smoc
目录号
NM-HU-252347
品系状态
在研
基因信息
基因名
B2M
品系描述
利用同源重组，将小鼠B2m基因进行人源化修饰。
*使用本品系发表的文献需注明: HLA-A24.2/B2M(M-NSG) mice (Cat. NO. NM-HU-252347) were purchased from Shanghai Model Organisms Center, Inc..
验证数据
Fig.1 Detection of hB2M and HLA-A,B,C expression on leukocytes in blood of WT NMG mice and F0(+) HLA-A24.2/B2M(NMG) mice by FACS.
Leukocytes were collected from wild-type NMG mice (male, 8 weeks old) and F0(+) HLA-A24.2/B2M humanized mice (male, 11 weeks old), and analyzed by flow cytometry with anti-HLA-ABC anti-mH2D, anti-mB2M, and anti-hB2M.
Abbr. WT, wild type.
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