hS100A9

品系全名

C57BL/6Smoc-S100a9tm1(hS100A9)Smoc

目录号

NM-HU-242497

品系状态

活体

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基因信息

基因名
S100a9

品系描述

利用同源重组,将小鼠S100a9基因进行人源化修饰。

验证数据

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Fig.1 Detection of S100A9 expression on neutrophil in spleen of WT C57BL/6 mice and HO hS100A9 mice by FACS. Leukocytes were collected from wild-type C57BL/6 mice (male, 15 weeks old) and homozygous hS100A9 humanized mice (male, famale, 15 weeks old), and analyzed by flow cytometry with anti-mS100A9 and anti-hS100A9. hS100A9 was exclusively detectable in hS100A9 humanized mice but not in wild-type mice. hS100A9 was exclusively detectable on neutrophil in hS100A9 humanized mice, whereas mS100A9 was exclusively detectable on neutrophil in wild-type C57BL/6 mice.


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